E-64

1 g

Artikelnummer:PPI 1810-1G
Menge:
Technische Daten
Format Peptide:white solid
Lagerung Peptide:-20 °C
Löslichkeit:15 mg/ml in 1:1 mixture water/ethanol
Molekulargewicht:357.41
Qualitätskontrolle:Analysis by HPLC
Reinheit (HPLC):> 97 %
Summenformel:C15H27N5O5
Target:Papain, Bromelain, Ficin, Cathepsin B, H, L, Tumor-Cathepsin, Calpain
CAS Nr.:66701-25-5
Stabilität:Lyoph.: 24 months, Stock solution: Aliquots 2 months
Klasse:Cysteine protease inhibitor
Synonyme:L-trans-Epoxysuccinyl-Leu-4-guanidinobutylamide, L-trans-Epoxysuccinyl-Leu-agmatine
Verfügbar in folgenden Ländern:world wide
Beschreibung

An irreversible, highly selective cysteine protease inhibitor. Shows no inhibition against serine proteases with an except of trypsin. Interacts with the Sn subsites of proteases. For in vivo studies the use of E-64 as a cysteine protease inhibitor is highly recommended because it has a specific inhibition, it is permeable in cells and tissues and has low toxicity. Inhibits activation-induced programmed cell death and restores defective immune responses in HIV+ donors.

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