Calpain Inhibitor I (MG101)
1 g
Artikelnummer: | PPI 3010-1G |
Technische Daten
Format Peptide: | white solid | Lagerung Peptide: | -20 °C | Löslichkeit: | 10 mg/ml in DMSO or ethanol | Molekulargewicht: | 383.53 | Qualitätskontrolle: | Analysis by HPLC | Reinheit (HPLC): | > 95 % | Summenformel: | C20H37N3O4 | Target: | Calpain I, Calpain II, Cathepsin B, Cathepsin L, Papain, weakly Cathepsin H and _-Chymotrypsin | CAS Nr.: | 110044-82-1 | Stabilität: | Lyoph.: 24 months, Stock solution: a few days | Klasse: | Serine protease inhibitor,Cysteine protease inhibitor | Synonyme: | ALLN, Ac-LLnL-CHO, MG-101, N-Acetyl-L-leucyl-L-leucyl-L-norleucinal, N-Acetyl-Leu-Leu-Norleu-al | Verfügbar in folgenden Ländern: | world wide |
Beschreibung
Calpain Inhibitor I has been observed to initiate apoptosis in tumor cell lines and HL-60 cells, but blocks dexamethasone-induced apoptosis in thymocytes and cycloheximide-induced apoptosis in metamyelocytes. Prevents nitric oxide production by activated macrophages. Protects against neuronal damage caused by hypoxia and ischemia.
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