p27Kip1

SX53G8, Ms, 1 ml Conc.

Artikelnummer:1-P2010-07
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Concentrate
Klon:SX53G8
Spezies:Mouse
Ig Unterklasse:IgG1/k
Immunogen:p27Kip1 Protein
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Tonsil
Lagerung AK:Aliquot and store at - 20 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Nuclear
Synonyme:Cyclin-dependent kinase inhibitor 1B, CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

p27 is a cyclin-dependent kinase inhibitor which regulates progression from G1 to S phase by binding and inhibiting cyclin-dependent kinases. Low expression has been associated with unfavorable prognosis in renal cell carcinoma, colon carcinoma, small breast carcinomas, non-small-cell lung carcinoma, hepatocellular carcinoma, multiple myeloma, lymph node metastases in Papillary carcinoma of the thyroid, and more aggressive phenotype in carcinoma of the cervix.

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