1D6, Ms

Technische Daten
Kontrolle:Bladder carcinoma
Zelluläre Lokalisation:Nuclear
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092) or ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Immunogen:Synthetic peptide of human c-Fos
Ig Unterklasse:IgG1/k
Status:Research Use Only (RUO)
Change(s) made:Complete revision
Synonyme:Activator protein 1, AP 1, C FOS, Cellular oncogene c fos, Cellular oncogene fos, FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS), FBJ murine osteosarcoma viral oncogene homolog, FBJ murine osteosarcoma viral v fos oncogene homolog, FBJ Osteosarcoma Virus, FOS, FOS protein, FOS_HUMAN, G0 G1 switch regulatory protein 7, G0/G1 switch regulatory protein 7, G0S7, Oncogene FOS, p55, proto oncogene c Fos, Proto oncogene protein c fos, Proto-oncogene c-Fos, v fos FBJ murine osteosarcoma viral oncogene homolog
Verfügbar in folgenden Ländern:worldwide

c-Fos is a proto-oncogene that plays an important role in many cellular functions and has been found to be overexpressed in a variety of cancers. It is involved in important cellular events, including cell proliferation, differentiation and survival which makes its dysregulation an important factor for cancer development. In osteosarcoma and endometrial carcinoma, c-Fos overexpression was associated with high-grade lesions and poor prognosis.