Tumor necrosis factor alpha/TNF alpha

Rb, 1 ml RTU

Artikelnummer:2-TU037-07
Menge:
Technische Daten
Reaktivität AK:Human, Mouse, Rabbit, Rat, please ask for further reactivities.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human TNF-alpha
Anwendung AK:IHC(p*) *reported as working on paraffin,IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Zelluläre Lokalisation:Secreted, membranous
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Synonyme:TNF-alpha, APC1, Cachectin, DIF, Differentiation inducing factor, Macrophage cytotoxic factor, MCF, Necrosin, TNF-a, TNF alpha, TNF, TNF Macrophage Derived, TNF Monocyte Derived, TNF Superfamily Member 2, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2, Tumor Necrosis Factor Precursor, Tumour Necrosis Factor Alpha, TNFSF1A.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

TNF alpha is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. It is produced by activated macrophages, CD4+ lymphocytes, NK cells, and neurons. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. It appears to be directly toxic to vascular endothelial cells. Currently TNF alpha is being evaluated in treatment of certain cancers and AIDS Related Complex.

Literatur

Kontakt