Troponin T


Technische Daten
Change(s) made:Complete revision
Status:Research Use Only (RUO)
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human Troponin T type 2
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Zelluläre Lokalisation:Cytoplasmic
Kontrolle:Cardiac muscle
Synonyme:Troponin T-C, Cardiac muscle troponin T, Cardiomyopathy dilated 1D (autosomal dominant), Cardiomyopathy hypertrophic 2, CMD1D, CMH2, CMPD2, cTnT, RCM3, TNNT 2, TNNT2, TnTC, Troponin T cardiac muscle, Troponin T type 2 (cardiac), Troponin T type 2 cardiac, Troponin T2, Troponin T2 cardiac, Troponin T.
Verfügbar in folgenden Ländern:worldwide

Troponin, or the troponin complex, is a complex of three regulatory proteins (troponin C, troponin I, and troponin T) that are integral to muscle contraction in skeletal muscle and cardiac muscle, but not smooth muscle.Troponin T binds to tropomyosin, interlocking them to form a troponin-tropomyosin complex. Troponin (cardiac I and T) are sensitive and specific indicators of damage to the heart muscle (myocardium). Troponins are increased in around 40 % of patients with critical illnesses such as sepsis. Cardiac troponin T and I can be used to monitor drug and toxin-induced cardiomyocyte toxicity.