Troponin I


Technische Daten
Change(s) made:Complete revision
Status:Research Use Only (RUO)
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human Troponin I
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Zelluläre Lokalisation:Cytoplasmic
Kontrolle:Cardiac muscle
Synonyme:Cardiac troponin I, Cardiomyopathy, familial hypertrophic, 7, included, CMD1FF, CMD2A, CMH7, cTnI, Familial hypertrophic cardiomyopathy 7, MGC116817, RCM1, Tn1, Tni, TNN I3, TNNC 1, TNNC1, TNNI3, Troponin I cardiac, Troponin I cardiac muscle, Troponin I cardiac muscle isoform, Troponin I type 3 cardiac, troponin I, cardiac 3, TroponinI.
Verfügbar in folgenden Ländern:worldwide

Troponin, or the troponin complex, is a complex of three regulatory proteins (troponin C, troponin I, and troponin T) that are integral to muscle contraction in skeletal muscle and cardiac muscle, but not smooth muscle. Troponin I binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Troponin (cardiac I and T) are sensitive and specific indicators of damage to the heart muscle (myocardium). Troponins are increased in around 40 % of patients with critical illnesses such as sepsis. In 2020, it was found that COVID-19 patients with severe disease had higher troponin I levels compared to those with milder disease.