Topoisomerase 2 alpha

Rb

Artikelnummer:TO014-H_RUO
Menge:
Technische Daten
Change(s) made:Complete revision
Status:Research Use Only (RUO)
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human TOPO II alpha
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092) or ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Nuclear, cytoplasmic
Kontrolle:Tonsil
Synonyme:DNA topoisomerase_alpha, DNA topoisomerase 2-alpha, DNA topoisomerase II, alpha isozyme, TOP2, TP2A, TOP2A, DNA topoisomerase II 170 kD, DNA topoisomerase II alpha isozyme, DNA Topoisomerase2, TOP 2A, TopII alpha, Topo II alpha, Topoisomerase DNA II alpha 170kDa, Topoisomerase II alpha 170 kDa.
Verfügbar in folgenden Ländern:worldwide
Beschreibung

TOP2A is an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It is a target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance.

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