Thyroperoxidase

Rb

Artikelnummer:TH060-H_RUO
Menge:
Technische Daten
Change(s) made:Complete revision
Status:Research Use Only (RUO)
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human TPO
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Zelluläre Lokalisation:Membranous
Kontrolle:Normal thyroid epithelial cells, thyroid tumor cells
Synonyme:MSA , PERT_HUMAN , TDH2A , Thyroid microsomal antigen , Thyroid peroxidase , Thyroperoxidase , TPO , TPX.
Verfügbar in folgenden Ländern:worldwide
Beschreibung

TPO is an enzyme expressed mainly in the thyroid where it is secreted into colloid. It is involved in the production of thyroxine (T4) or triiodothyronine (T3), the thyroid hormones. TPO is stimulated by TSH, which upregulates gene expression, and is inhibited by the thioamide drugs. In diagnostic IHC, the expression of thyroid peroxidase is lost in papillary thyroid carcinoma.

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