Tau tubulin kinase 1/TTBK1
Rb, 3 ml RTU
Technische Daten
Lagerung AK: | Store at 2 - 8 °C. Do not use after expiration date indicated on the vial. | Reaktivität AK: | Human, Mouse, Rat, please ask for further reactivities. | Format AK: | Ready-to-use | Klon: | Polyclonal | Spezies: | Rabbit | Ig Unterklasse: | IgG | Immunogen: | Synthetic peptide | Anwendung AK: | IHC(p*) *reported as working on paraffin,IHC(f) | Fixierung: | 1) NOTOXhisto 2) Formalin | Kontrolle: | Human placenta tissue | Synonyme: | BDTK, Brain derived tau kinase, Brain-derived tau kinase, KIAA1855, Tau tubulin kinase 1, Tau-tubulin kinase 1, TTBK1, TTBK1_HUMAN. | Verfügbar in folgenden Ländern: | world wide | Status: | RUO |
Beschreibung
TTBK1 (tau tubulin kinase 1) is a serine/threonine kinase that is localized to the cytoplasm and expressed at high levels in brain and at lower levels in testis and spinal cord. It can phosphorylate Tau (a protein involved in tubulin polymerization) on threonine, tyrosine and serine residues. Phosphorylation of Tau causes its aggregation and subsequent loss of function, suggesting an important role for TTBK1 in the control of tubulin dynamics.
|