Tau tubulin kinase 1/TTBK1

Rb, 3 ml RTU

Artikelnummer:2-TA024-10
Menge:
Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Reaktivität AK:Human, Mouse, Rat, please ask for further reactivities.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide
Anwendung AK:IHC(p*) *reported as working on paraffin,IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Human placenta tissue
Synonyme:BDTK, Brain derived tau kinase, Brain-derived tau kinase, KIAA1855, Tau tubulin kinase 1, Tau-tubulin kinase 1, TTBK1, TTBK1_HUMAN.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

TTBK1 (tau tubulin kinase 1) is a serine/threonine kinase that is localized to the cytoplasm and expressed at high levels in brain and at lower levels in testis and spinal cord. It can phosphorylate Tau (a protein involved in tubulin polymerization) on threonine, tyrosine and serine residues. Phosphorylation of Tau causes its aggregation and subsequent loss of function, suggesting an important role for TTBK1 in the control of tubulin dynamics.

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