Tartrate resistant acid phosphatase/TRAP

Rb, 1 ml Conc.

Artikelnummer:1-TA008-07
Menge:
Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Cytoplasmic
Reaktivität AK:Human, others not tested.
Format AK:Concentrate
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human Tartrate Resistant Acid Phosphatase type 5
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Hairy cell leukemia
Synonyme:Type 5 acid phosphatase, Acid phosphatase 5 tartrate resistant, ACP5, PPA5_HUMAN, T5ap, Tartrate resistant acid ATPase, Tartrate resistant acid phosphatase type 5, Tartrate resistant acid phosphatase type 5 precursor, Tartrate-resistant acid ATPase, Tartrate-resistant acid phosphatase type 5, TR AP, TR-AP, TrATPase, Type 5 acid phosphatase.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

Tartrate-resistant acid phosphatase is a 35 kDa glycosylated monomeric metalloenzyme expressed in mammals. It is highly expressed by osteoclasts, activated macrophages, and neurons. Expression is increased in certain pathological conditions, including leukaemic reticuloendotheliosis (hairy cell leukaemia), Gaucher’s disease, HIV-induced encephalopathy, osteoclastoma and osteoporosis, and metabolic bone diseases. The histochemical identification of hairy cell leukemia via tartrate-resistant acid phosphatase assay has been a standard for over two decades because this antibody labels the cells of hairy cell leukemia with a high degree of sensitivity and specificity.

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