Tartrate resistant acid phosphatase/TRAP

Ms, 0.1 ml Conc.

Technische Daten
Lagerung AK:Aliquot and store at - 20 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Cytoplasmic
Reaktivität AK:Human, others not tested.
Format AK:Concentrate
Ig Unterklasse:IgG2/b
Immunogen:Tartrate-resistant Acid Phosphatase
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Hairy cell leukemia
Synonyme:TRAcP, acid phosphatase 5, tartrate resistant, ACP5, TRAP, SPENCDI
Verfügbar in folgenden Ländern:world wide

Tartrate-resistant acid phosphatase is a 35 kDa glycosylated monomeric metalloenzyme expressed in mammals. It is highly expressed by osteoclasts, activated macrophages, and neurons. Expression is increased in certain pathological conditions, including leukaemic reticuloendotheliosis (hairy cell leukaemia), Gaucher’s disease, HIV-induced encephalopathy, osteoclastoma and osteoporosis, and metabolic bone diseases. The histochemical identification of hairy cell leukemia via tartrate-resistant acid phosphatase assay has been a standard for over two decades because this antibody labels the cells of hairy cell leukemia with a high degree of sensitivity and specificity.