TROP2
Rb
Artikelnummer: | TU022-H_RUO |
Technische Daten
Change(s) made: | Complete revision | Status: | Research Use Only (RUO) | Spezies: | Rabbit | Ig Unterklasse: | IgG | Immunogen: | Synthetic peptide of human Trop2 protein | Vorbehandlung: | ProTaqs® Antigen Enhancer IV (Cat. No. 401602392) | Zelluläre Lokalisation: | Membranous | Kontrolle: | Placenta, papillary thyroid carcinoma | Synonyme: | Cell surface glycoprotein Trop 2, Cell surface glycoprotein Trop-2, Cell surface glycoprotein Trop2, Epithelial glycoprotein 1, GA733 1, GA7331, M1S 1, M1S1, Membrane component chromosome 1 surface marker 1, Pancreatic carcinoma marker protein GA733 1, Pancreatic carcinoma marker protein GA733-1, Pancreatic carcinoma marker protein GA7331, TACD 2v TACD2_HUMAN, TACSTD 2, TACSTD2, Trop 2, Trop2, Tumor associated calcium signal transducer 2 precursor, Tumor-associated calcium signal transducer 2. | Verfügbar in folgenden Ländern: | worldwide |
Beschreibung
TACD2 is a transmembrane glycoprotein originally identified in trophoblasts. It functions to maintain epithelial barrier function and localization of tight junctional proteins. It acts as a cell surface receptor that transduces intracellular calcium, but its endogenous ligand has not been identified. Expression is broadly observed in many normal tissues and is frequently overexpressed in a variety of tumors including papillary thyroid carcinoma (PTC).
|