Technische Daten
Change(s) made:Complete revision
Status:Research Use Only (RUO)
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human Trop2 protein
Vorbehandlung:ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Membranous
Kontrolle:Placenta, papillary thyroid carcinoma
Synonyme:Cell surface glycoprotein Trop 2, Cell surface glycoprotein Trop-2, Cell surface glycoprotein Trop2, Epithelial glycoprotein 1, GA733 1, GA7331, M1S 1, M1S1, Membrane component chromosome 1 surface marker 1, Pancreatic carcinoma marker protein GA733 1, Pancreatic carcinoma marker protein GA733-1, Pancreatic carcinoma marker protein GA7331, TACD 2v TACD2_HUMAN, TACSTD 2, TACSTD2, Trop 2, Trop2, Tumor associated calcium signal transducer 2 precursor, Tumor-associated calcium signal transducer 2.
Verfügbar in folgenden Ländern:worldwide

TACD2 is a transmembrane glycoprotein originally identified in trophoblasts. It functions to maintain epithelial barrier function and localization of tight junctional proteins. It acts as a cell surface receptor that transduces intracellular calcium, but its endogenous ligand has not been identified. Expression is broadly observed in many normal tissues and is frequently overexpressed in a variety of tumors including papillary thyroid carcinoma (PTC).