T cell restricted intracellular antigen 1/TIA1
Rb, 7 ml RTU
Technische Daten
Lagerung AK: | Store at 2 - 8 °C. Do not use after expiration date indicated on the vial. | Zelluläre Lokalisation: | Cytoplasmic | Reaktivität AK: | Human, others not tested. | Format AK: | Ready-to-use | Klon: | Polyclonal | Spezies: | Rabbit | Ig Unterklasse: | IgG | Immunogen: | Synthetic peptide of human TIA1 | Anwendung AK: | IHC(p),IHC(f) | Fixierung: | 1) NOTOXhisto 2) Formalin | Kontrolle: | Spleen | Synonyme: | Cytotoxic granule associated RNA binding protein 1, Cytotoxic granule associated RNA binding protein, mTIA-1, Nucleolysin TIA 1 isoform p40, Nucleolysin TIA-1 isoform p40, Nucleolysin TIA1 isoform p40, p40 TIA 1, p40-TIA-1, RNA binding protein TIA 1, RNA binding protein TIA1, RNA-binding protein TIA-1, T-cell-restricted intracellular antigen-1, TIA 1, TIA 1 cytotoxic granule associated RNA binding protein, TIA-1, TIA1, TIA1 cytotoxic granule associated RNA binding protein, TIA1 cytotoxic granule associated RNA binding protein like 1, TIA1 protein, TIA1_HUMAN, TIAL1, TIAR. | Verfügbar in folgenden Ländern: | world wide | Status: | RUO |
Beschreibung
TIA1 possesses nucleolytic activity against cytotoxic lymphocyte target cells and may be involved in the induction of apoptosis. The antibody labels cytotoxic T cells and natural killer cells. Expression is found in T-cell lymphoma, large granular lymphocyte leukemia and hairy cell leukemia. The expression in T cell malignancies may help in differentiating LGL leukemia (high expression) from T cell lymphocytosis and other T cell diseases (low expression).
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