T cell restricted intracellular antigen 1/TIA1

T cell restricted intracellular antigen 1/TIA1

Rb, 7 ml RTU

Artikelnummer:2-T0018-13
Menge:
Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Cytoplasmic
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human TIA1
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Spleen
Synonyme:Cytotoxic granule associated RNA binding protein 1, Cytotoxic granule associated RNA binding protein, mTIA-1, Nucleolysin TIA 1 isoform p40, Nucleolysin TIA-1 isoform p40, Nucleolysin TIA1 isoform p40, p40 TIA 1, p40-TIA-1, RNA binding protein TIA 1, RNA binding protein TIA1, RNA-binding protein TIA-1, T-cell-restricted intracellular antigen-1, TIA 1, TIA 1 cytotoxic granule associated RNA binding protein, TIA-1, TIA1, TIA1 cytotoxic granule associated RNA binding protein, TIA1 cytotoxic granule associated RNA binding protein like 1, TIA1 protein, TIA1_HUMAN, TIAL1, TIAR.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

TIA1 possesses nucleolytic activity against cytotoxic lymphocyte target cells and may be involved in the induction of apoptosis. The antibody labels cytotoxic T cells and natural killer cells. Expression is found in T-cell lymphoma, large granular lymphocyte leukemia and hairy cell leukemia. The expression in T cell malignancies may help in differentiating LGL leukemia (high expression) from T cell lymphocytosis and other T cell diseases (low expression).

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