Special AT rich sequence binding protein 2/SATB2

Rb, 1 ml Conc.

Artikelnummer:1-SP005-07
Menge:
Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Nuclear
Reaktivität AK:Human, others not tested.
Format AK:Concentrate
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human SATB2
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Colon, colorectal cancer
Synonyme:DNA binding protein SATB2, DNA-binding protein SATB2, FLJ21474, FLJ32076, KIAA1034, MGC119474, MGC119477, SATB family member 2, SATB homeobox 2, SATB2, SATB2_HUMAN, Special AT rich sequence binding protein 2, Special AT-rich sequence-binding protein 2.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

SATB2 is a nuclear matrix protein that influences craniofacial formation mechanisms, such as jaw and palate development, and is part of a transcriptional network regulating skeletal development and osteoblast differentiation. It is highly expressed in adult and fetal brain, and weak expressed in liver, kidney, and spinal cord as well as some brain regions. Defects in the gene encoding SATB2 are the cause of cleft palate manifested in conjunction with severe mental retardation.

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