SMAD4

B-8, Ms

Artikelnummer:MO032-H_RUO
Menge:
Technische Daten
Change(s) made:Complete revision
Status:Research Use Only (RUO)
Spezies:Mouse
Ig Unterklasse:IgG1
Immunogen:Full length Smad4 of human origin
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Zelluläre Lokalisation:Nuclear
Kontrolle:Pancreatic adenocarcinoma
Synonyme:Mothers against decapentaplegic homolog 4, (Small) Mothers Against Decapentaplegic, Deleted in Pancreatic Carcinoma, Deleted in pancreatic carcinoma locus 4, Deletion target in pancreatic carcinoma 4, DPC 4, DPC4, hSMAD4, JIP, MAD homolog 4, MAD mothers against decapentaplegic Drosophila homolog 4, MAD mothers against decapentaplegic homolog 4, MADH 4, MADH4, Med, Medea, Mothers against decapentaplegic homolog 4, Mothers against DPP homolog 4, OTTHUMP00000163548, Smad 4, SMAD family member 4, SMAD mothers against DPP homolog 4.
Verfügbar in folgenden Ländern:worldwide
Beschreibung

SMAD family member 4, also known as SMAD4, is a protein that is involved in cell signaling. It functions as a transcription factor and is a member of the TGFbeta superfamily. It is mutated in many cancers: multiploid colorectal cancer, pancreatic carcinoma and juvenile polyposis syndrome (JPS) which includes a greater risk of developing gastrointestinal cancers, in particular colon cancer. Smad 4 is a member of the Mothers Against Dpp (MAD)-related family of proteins.

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