Technische Daten
Change(s) made:Complete revision
Status:Research Use Only (RUO)
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human S100A9
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Zelluläre Lokalisation:Cytoplasmic, nuclear
Kontrolle:Spleen, inflammatory tissue
Synonyme:MRP14, CFAG, Leukocyte L1 complex heavy chain, 60B8AG, CAGB, Calgranulin B, CGLB, L1AG, Leukocyte L1 complex heavy chain, LIAG, MIF, Migration inhibitory factor related protein 14, NIF, P14.
Verfügbar in folgenden Ländern:worldwide

S100A9 is a member of the S100 family of proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A9 may function in the inhibition of casein kinase and has been implicated in the abnormal differentiation of myeloid cells in the stroma of cancer, and to leukemia progression. Outside of malignancy, S100A9 in association with its dimerization partner S100A8 signals for lymphocyte recruitment in sites of inflammation. S100A9/A8 are also regarded as marker proteins for a number of inflammatory diseases in humans, especially in rheumatoid arthritis and inflammatory bowel disease.