Technische Daten
Change(s) made:Complete revision
Status:Research Use Only (RUO)
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human S100A8
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Zelluläre Lokalisation:Cytoplasmic, membranous
EK Distributor €:-
EK Liste €:599
Synonyme:60B8Ag, AI323541, B8Ag, BEE11, CAGA, Calgranulin-A, Calprotectin L1L subunit, Calprotectin, included, CFAG, CGLA, Chemotactic cytokine CP-10, CP-10, Cystic fibrosis antigen, L1Ag, Leukocyte L1 complex light chain, MA387, MIF, Migration inhibitory factor-related protein 8, Myeloid-related protein 8, Neutrophil cytosolic 7 kDa protein, NIF, p8, Pro-inflammatory S100 cytokine, Protein S100-A8, S100 calcium binding protein A8 (calgranulin A), S100 calcium binding protein A8, S100A8, S100A8/S100A9 complex, included, Urinary stone protein band A, MRP8.
Verfügbar in folgenden Ländern:worldwide

S100A8 is a member of the S100 family of proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A8 may function in the inhibition of casein kinase and as a cytokine. Outside of malignancy, S100A8 in association with its dimerization partner S100A9 signals for lymphocyte recruitment in sites of inflammation. S100A8/A9 are also regarded as marker proteins for a number of inflammatory diseases in humans, especially in rheumatoid arthritis and inflammatory bowel disease.