Technische Daten
Change(s) made:Complete revision
Status:Research Use Only (RUO)
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human S100A4
Vorbehandlung:ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Cytoplasmic
Kontrolle:Tonsil, breast carcinoma
Synonyme:18A2, 42A, Calcium protein, Calvasculin, CAPL, Malignant transformation suppression 1, Metastasin, MTS1, Mts1 protein, Murine placental homolog , P9KA antibody PEL98, Placental calcium binding protein, Protein Mts1, Protein S100 A4 , S100 calcium binding protein A4.
Verfügbar in folgenden Ländern:worldwide

S100A4 is a member of the S100 family of proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. S100A4 is highly associated with components of the cytoskeleton and when this gene is upregulated, it changes the cellÍs morphology, making it more susceptible to invasion from proteins, such as cathepsin B and cyclin B1, that contribute to metastasis.[