Technische Daten
Change(s) made:Complete revision
Status:Research Use Only (RUO)
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human S100A1
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092) or ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Cytoplasmic, nuclear
Kontrolle:Heart muscle, papillary renal cell carcinoma
Synonyme:S-100 protein alpha subunit, S-100 protein alpha chain, Protein S100-A1, S100 calcium-binding protein A1 , S100 alpha , Protein S100-A1 , S-100 protein alpha chain , S-100 protein subunit alpha , S100 , S100 Calcium Binding Protein A1 , S100 calcium-binding protein A1 , S100 protein alpha polypeptide , S100A , S100A1 , S10A1_HUMAN.
Verfügbar in folgenden Ländern:worldwide

S100A1 is a member of the S100 family of proteins that contains 2 EF-hand calcium-binding motifs and that is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. It is expressed in the cytoplasm and/or nuclei of cardiac and skeletal muscle as well as neuronal cells. S100A1 is useful in distinguishing between renal cell carcinomas (protein is present) and chromophobe renal cell carcinomas (protein is absent). It is also a specific and sensitive marker for nephrogenic adenoma.