S100 beta

Rb, 0.5 ml Conc.

Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Concentrate
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human S100 beta C-terminal
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Zelluläre Lokalisation:Cytoplasmic
Kontrolle:Skin, melanoma
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Synonyme:NEF, Protein S100 B, Protein S100-B, S 100 calcium binding protein beta chain, S 100 protein beta chain, S 100 protein beta subunit, S-100 protein beta chain, S-100 protein subunit beta, S100, S100 calcium binding protein B, S100 calcium binding protein beta (neural), S100 calcium binding protein beta chain, S100 calcium-binding protein B, S100 protein beta chain, S100B, S100B_HUMAN, S100beta.
Verfügbar in folgenden Ländern:world wide (except US)

S100 Beta is a member of the S100 family of proteins and is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. The protein is expressed in glial cells of the central and peripheral nervous system, chondrocytes, adipocytes and melanocytes. The antibody S100 Beta is a useful marker for diagnosis of melanoma and tumors of
nerves system.


[1] Donato R (1999): Functional roles of S100 betas, calcium-binding proteins of the EF-hand type. Biochim Biophys Acta. 1450(3):191-231.
[2] Clarkson KS, Sturdgess IC and Molyneux AJ (2001): The usefulness of tyrosinase in the immunohistochemical assessment of melanocytic lesions: a comparison of the novel T311 antibody (anti-tyrosinase) with S-100, HMB45, and A103 (anti-melan-A). J Clin Pathol. 54(3):196-200.
[3] Smith SP and Shaw GS (1998): A novel calciumsensitive switch revealed by the structure of human S100B in the calcium-bound form. Structure. 6(2):211-22.
[4] HydŽn H, Lange PW (1970): S100 brain protein: correlation with behavior. Proc Natl Acad Sci U S A. 67(4):1959-66.