Progesterone receptor/PR

Rb, 0.5 ml Conc.

Artikelnummer:1-PR026-05
Menge:
Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Kontrolle:Breast, breast cancer
Zelluläre Lokalisation:Nuclear
Fixierung:1) NOTOXhisto 2) Formalin
Anwendung AK:IHC(p),IHC(f)
Immunogen:Synthetic peptide of human progesterone receptor N-terminal
Ig Unterklasse:IgG
Spezies:Rabbit
Klon:Polyclonal
Format AK:Concentrate
Reaktivität AK:Human, others not tested.
Synonyme:NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, PR, PRA, PRB, Progesterone receptor, Progestin receptor form A, Progestin receptor form B.
Verfügbar in folgenden Ländern:world wide (except US)
Status:IVD
Beschreibung

Progesterone receptor is a hormone receptor activated by the steroid hormone progesterone. This antibody is a prognostic indicator in breast carcinoma. For human nuclear progesterone receptor. Staining of nuclei of carcinoma cells and hyperplastic mammary epithelium.

Literatur

[1] Mulac-Jericevic B, Conneely OM (2004): Reproductive tissue selective actions of progesterone receptors. Reproduction. 128(2): 139-146.
[2] Duffy MJ, Harbeck N, Nap M et al. (2017): Clinical use of biomarkers in breast cancer: Updated guidelines from the European Group on Tumor Markers (EGTM). Eur J Cancer. 75: 284-298.
[3] Schettini F, Buono G, Cardalesi C et al. (2016): Hormone Receptor/Human Epidermal Growth Factor Receptor 2-positive breast cancer: Where we are now and where we are going. Cancer Treat Rev. 46: 20-26.
[4] Wei LL, Miner R (1994): Evidence for the existence of a third progesterone receptor protein in human breast cancer cell line T47D. Cancer Res. 54(2): 340-343.

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