Progesterone receptor/PR
Rb, 0.5 ml Conc.
Technische Daten
| Lagerung AK: | Store at 2 - 8 °C. Do not use after expiration date indicated on the vial. | | Kontrolle: | Breast, breast cancer | | Zelluläre Lokalisation: | Nuclear | | Fixierung: | 1) NOTOXhisto 2) Formalin | | Anwendung AK: | IHC(p),IHC(f) | | Immunogen: | Synthetic peptide of human progesterone receptor N-terminal | | Ig Unterklasse: | IgG | | Spezies: | Rabbit | | Klon: | Polyclonal | | Format AK: | Concentrate | | Reaktivität AK: | Human, others not tested. | | Synonyme: | NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, PR, PRA, PRB, Progesterone receptor, Progestin receptor form A, Progestin receptor form B. | | Verfügbar in folgenden Ländern: | world wide (except US) | | Status: | IVD |
Beschreibung
Progesterone receptor is a hormone receptor activated by the steroid hormone progesterone. This antibody is a prognostic indicator in breast carcinoma. For human nuclear progesterone receptor. Staining of nuclei of carcinoma cells and hyperplastic mammary epithelium.
Literatur
[1] Mulac-Jericevic B, Conneely OM (2004): Reproductive
tissue selective actions of progesterone receptors.
Reproduction. 128(2): 139-146.
[2] Duffy MJ, Harbeck N, Nap M et al. (2017): Clinical use
of biomarkers in breast cancer: Updated guidelines from
the European Group on Tumor Markers (EGTM). Eur J
Cancer. 75: 284-298.
[3] Schettini F, Buono G, Cardalesi C et al. (2016):
Hormone Receptor/Human Epidermal Growth Factor
Receptor 2-positive breast cancer: Where we are now
and where we are going. Cancer Treat Rev. 46: 20-26.
[4] Wei LL, Miner R (1994): Evidence for the existence of
a third progesterone receptor protein in human breast
cancer cell line T47D. Cancer Res. 54(2): 340-343.
|
