Pancreatic and duodenal homeobox 1/PDX1

Rb, 0.1 ml Conc.

Artikelnummer:1-PA027-02
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Concentrate
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human PDX1
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Human pancreas & duodenum tissue
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Nuclear
Synonyme:PDX-1, pancreatic and duodenal homeobox 1, Insulin promoter factor 1, IPF-1, Islet/duodenum homeobox-1, IDX-1, Somatostatin-transactivating factor 1, STF-1, Insulin upstream factor 1, IUF-1, Glucose-sensitive factor, GSF
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

PDX1 is a protein that activates transcription of insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2. It is a key regulator of islet peptide hormone expression and plays an essential role in pancreatic development. Mutations in this gene may be involved in several disorders of the pancreas or in diabetes mellitus. Expression is found in duodenum and pancreas.

Literatur

Kontakt