PNL2/Melanoma

PNL2, Ms, 3 ml RTU

Artikelnummer:2-PN002-10
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:PNL2
Spezies:Mouse
Ig Unterklasse:IgG1
Immunogen:PNL2
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Melanoma
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Cytoplasmic
Synonyme:Antigen LB39 AA, Antigen SK29 AA, CMM 1, CMM, CMM1, Cutaneous Malignant Melanoma Dysplastic Nevus, Dysplastic Nevus Syndrome, FAMMM, MART1, melan A, Melan A protein, Melanoma antigen recognized by T-cells 1, MLM, Monophenol monooxygenase, Tumor rejection antigen AB, tyrosinase
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

PNL2 is a novel monoclonal antibody that labels melanocytes in the cytoplasm and plasma membrane and tumors derived from these cells (melanomas and clear cell sarcomas). Antibodies against PNL2, Melan-A and HMB-45 stain most clear cell sarcoma cells and a few cells in angiomyolipomas and lymphangioleiomyomatosis; a panel of antibodies, including HMB-45, MART-1, Tyrosinase, and MiTF enables differential diagnosis. Anti-PNL2 may be most useful because of its high sensitivity for metastatic melanoma, and combined with antibodies against S-100 and HMB-45 is a highly sensitive and specific marker for mucosal melanoma.

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