PHOX2B

Rb

Artikelnummer:PA004-H_RUO
Menge:
Technische Daten
Change(s) made:Complete revision
Status:Research Use Only (RUO)
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human PHOX2B
Vorbehandlung:ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Nuclear
Kontrolle:Neuroblastoma
Synonyme:NBPHOX, Neuroblastoma paired type homeobox protein, Neuroblastoma Phox, Paired like homeobox 2b, Paired mesoderm homeobox protein 2B, Paired-like homeobox 2B, PHOX 2B, PHOX 2B homeodomain protein, PHOX2B, PHOX2B homeodomain protein, PHX2B_HUMAN, PMX 2B, PMX2B.
Verfügbar in folgenden Ländern:worldwide
Beschreibung

Paired like homeobox 2b, also known as PHOX2B, neuroblastoma Phox or NBPhox, is a transcription factor that is expressed exclusively in the nervous system. It is found in most neurons that control the viscera (cardiovascular, digestive and respiratory systems) and is also required for their differentiation. PHOXB2 is a marker of neural crest derivation, has been shown to be sensitive and specific for undifferentiated neuroblastoma, enabling identification where other markers fail to recognize neuroblastoma among various different small round blue cell tumors of childhood.

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