PDX1
Rb
Artikelnummer: | PA027-H_RUO |
Technische Daten
Change(s) made: | Complete revision | Status: | Research Use Only (RUO) | Spezies: | Rabbit | Ig Unterklasse: | IgG | Immunogen: | Synthetic peptide of human PDX1 | Vorbehandlung: | ProTaqs® Antigen Enhancer I (Cat. No. 401602092) | Zelluläre Lokalisation: | Nuclear | Kontrolle: | Pancreas, duodenum | Synonyme: | PDX-1, pancreatic and duodenal homeobox 1, Insulin promoter factor 1, IPF-1, Islet/duodenum homeobox-1, IDX-1, Somatostatin-transactivating factor 1, STF-1, Insulin upstream factor 1, IUF-1, Glucose-sensitive factor, GSF | Verfügbar in folgenden Ländern: | worldwide |
Beschreibung
PDX1 is a protein that activates transcription of insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2. It is a key regulator of islet peptide hormone expression and plays an essential role in pancreatic development. Mutations in this gene may be involved in several disorders of the pancreas or in diabetes mellitus. Expression is found in duodenum and pancreas.
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