PDX1

Rb

Artikelnummer:PA027-H_RUO
Menge:
Technische Daten
Change(s) made:Complete revision
Status:Research Use Only (RUO)
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human PDX1
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Zelluläre Lokalisation:Nuclear
Kontrolle:Pancreas, duodenum
Synonyme:PDX-1, pancreatic and duodenal homeobox 1, Insulin promoter factor 1, IPF-1, Islet/duodenum homeobox-1, IDX-1, Somatostatin-transactivating factor 1, STF-1, Insulin upstream factor 1, IUF-1, Glucose-sensitive factor, GSF
Verfügbar in folgenden Ländern:worldwide
Beschreibung

PDX1 is a protein that activates transcription of insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2. It is a key regulator of islet peptide hormone expression and plays an essential role in pancreatic development. Mutations in this gene may be involved in several disorders of the pancreas or in diabetes mellitus. Expression is found in duodenum and pancreas.

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