Octamer binding transcription factor 2/OCT2

Rb, 1 ml Conc.

Artikelnummer:1-OC005-07
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Concentrate
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human OCT2
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Tonsil, lymphoma
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Nucelar, cytoplasmic may be observed
Synonyme:organic cation transporter OCT2, POU domain, class 2, transcription factor 2, Octamer-binding transcription factor 2, Oct-2, OTF-2, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, POU2F2, NF A2, Oct 2.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

Oct-2 is a octamer transcription factor which is part of the POU family regulating B-cell-specific genes. The level of its expression can be used as a marker of B-cell lineage and differentiation. High expression is found in germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells. Various lymphomas are also positive for this marker including the following: B-chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, T-cell rich B-cell lymphoma, nodular lymphocyte predominant Hodgkin lymphoma, classic Hodgkin lymphoma.

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