Technische Daten
Change(s) made: | Complete revision | Status: | In Vitro Diagnostic Use (IVD) | Spezies: | Rabbit | Ig Unterklasse: | IgG | Immunogen: | Synthetic peptide of human OCT-4 | Vorbehandlung: | ProTaqs® Antigen Enhancer I (Cat. No. 401602092) | Zelluläre Lokalisation: | Nuclear | Kontrolle: | Seminoma | Synonyme: | POU domain, class 5, transcription factor 1,Oct-3/4, Oct-4A, Oct4A, Oct 4A, Octamer-binding transcription, factor 3, Octamer-4, Octamer-3, Oct-3, NF-A3, Otf-3, Otf3, POU5F1, Octamer binding transcription factor 4 | Verfügbar in folgenden Ländern: | worldwide |
Beschreibung
Oct-4 is a octamer transcription factor that maintains and regulates pluripotency in embryonic stem and germ cells. It is frequently used as a marker for undifferentiated cells and has a very high sensitivity and specificity in seminoma/dysgerminoma, embryonal carcinoma and the germ cell component of gonadoblastoma by nuclear immunostaining.
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