Neutrophil elastase

Rb, 0.1 ml Conc.

Artikelnummer:1-NE179-02
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Concentrate
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human Neutrophil Elastase
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Spleen, granulocytic leukemia
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Cytoplasmic
Synonyme:Bone Marrow Serine Protease, ELA 2, ELA2, ELANE, Elastase 2, Elastase 2 neutrophil, Elastase neutrophil expressed, Elastase-2, ELNE_HUMAN, GE antibody Granulocyte derived elastase, HLE, HNE, Human leukocyte elastase, Leukocyte elastase, Leukocyte Elastase Precursor, Medullasin, NE antibody Neutrophil elastase, Neutrophill elastase, PMN E, PMN Elastase, Polymorphonuclear elastase, SCN1, Serine protease, SERP1.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

Elastases are serine proteases that hydrolyze many proteins in addition to elastin. Neutrophil elastase hydrolyzes proteins within neutrophil lysosomes as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases; mutations are associated with cyclic neutropenia and severe congenital neutropenia.

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