Neutrophil elastase


Technische Daten
Change(s) made:Complete revision
Status:Research Use Only (RUO)
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human Neutrophil Elastase
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Zelluläre Lokalisation:Cytoplasmic
Kontrolle:Spleen, granulocytic leukemia
Synonyme:Bone Marrow Serine Protease, ELA 2, ELA2, ELANE, Elastase 2, Elastase 2 neutrophil, Elastase neutrophil expressed, Elastase-2, ELNE_HUMAN, GE antibody Granulocyte derived elastase, HLE, HNE, Human leukocyte elastase, Leukocyte elastase, Leukocyte Elastase Precursor, Medullasin, NE antibody Neutrophil elastase, Neutrophill elastase, PMN E, PMN Elastase, Polymorphonuclear elastase, SCN1, Serine protease, SERP1.
Verfügbar in folgenden Ländern:worldwide

Elastases are serine proteases that hydrolyze many proteins in addition to elastin. Neutrophil elastase hydrolyzes proteins within neutrophil lysosomes as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases; mutations are associated with cyclic neutropenia and severe congenital neutropenia.