Neurofilament

2F11, Ms, 3 ml RTU

Artikelnummer:2-NE084-10
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:2F11
Spezies:Mouse
Ig Unterklasse:IgG1/k
Immunogen:Neurofilament
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Brain
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Cytoplasmic
Synonyme:68 kDa neurofilament protein, CMT1F, CMT2E, FLJ53642, Light molecular weight neurofilament protein, NEFL, Neurofilament light, Neurofilament light polypeptide 68kDa, Neurofilament protein, light chain, Neurofilament subunit NF L, Neurofilament triplet L protein, NF-L, NF68, NFL
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

Neurofilaments are a type of intermediate filament that serve as major elements of the cytoskeleton supporting the axon cytoplasm. Neurofilaments usually contain three intermediate filament proteins: L, M, and H (68/70, 160, and 200 kDa) which occur in the central and peripheral nervous system and are usually neuron specific. This antibody stains an antigen localized in a number of neural, neuroendocrine, and endocrine tumors, such as neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas and neuroblastomas, paragangliomas, as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament. This antibody specifically recognizes the light neurofilament subunit or NF-L (68 kDa); it is not cross-reactive with other intermediate filament proteins.

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