Myogenic differentiation 1/MyoD1

Rb, 7 ml RTU

Artikelnummer:2-MY049-13
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human MyoD1
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Rhabdomyosarcoma
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Nuclear
Synonyme:Myogenic differentiation 1, AI503393, bHLHc1, MD1, MGC156574, MYF3, MYOD, MYOD1, PUM.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

MyoD1 is a protein with a key role in regulating muscle differentiation by inducing cell cycle arrest. The protein is also involved in muscle regeneration. MyoD1 is expressed in developing skeletal muscle tissue but faintly in adult skeletal muscle. In abnormal tissues, it labels tumor cell in Rhabdomyosarcoma, thus antibody to MyoD1 has been useful to differentiate rhabdomyosarcomas from other tumors. It is a sensitive and specific marker for myogenic differentiation.

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