MyoD1

Rb

Artikelnummer:MY049-H
Menge:
Technische Daten
Change(s) made:Complete revision
Status:In Vitro Diagnostic Use (IVD)
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human MyoD1
Vorbehandlung:ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Nuclear
Kontrolle:Rhabdomyosarcoma
Synonyme:Myogenic differentiation 1, AI503393, bHLHc1, MD1, MGC156574, MYF3, MYOD, MYOD1, PUM.
Verfügbar in folgenden Ländern:worldwide
Beschreibung

MyoD1 is a protein with a key role in regulating muscle differentiation by inducing cell cycle arrest. The protein is also involved in muscle regeneration. MyoD1 is expressed in developing skeletal muscle tissue but faintly in adult skeletal muscle. In abnormal tissues, it labels tumor cell in Rhabdomyosarcoma, thus antibody to MyoD1 has been useful to differentiate rhabdomyosarcomas from other tumors. It is a sensitive and specific marker for myogenic differentiation.

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