Multiple myeloma oncogene 1/MUM1

Rb, 3 ml RTU

Artikelnummer:2-MU048-10
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human MUM1
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Human lymphoma and Human tonsil tissues
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Nuclear
Synonyme:EXPAND1, FLJ14868, FLJ22283, HSPC211, Melanoma associated antigen (mutated) 1, Melanoma ubiquitous mutated protein, MGC131891, MGC163315, MUM 1, MUM-1, MUM1, MUM1_HUMAN, Mutated melanoma associated antigen 1, Mutated melanoma-associated antigen 1, Protein expandere, PWWP domain containing protein MUM1, PWWP domain-containing protein MUM1.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

MUM1 is a transcriptional activator that binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter as well as immunoglobulin lambda light chain enhancer, together with PU.1. It is expressed in the nuclei and cytoplasm of plasma cells, a subset of B-cells in the light zone of the germinal center, activated T-cells and a wide spectrum of related hematolymphoid neoplasms derived from these cells. This antibody is used to detect lymphoid malignancies and Hodgkin’s and Reed-Sternberg cells of classic Hodgkin’s disease in combination with anti-CD30.

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