Mothers against decapentaplegic homolog 4/SMAD4

B-8, Ms, 0.1 ml Conc.

Artikelnummer:1-MO032-02
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Concentrate
Klon:B-8
Spezies:Mouse
Ig Unterklasse:IgG1
Immunogen:Full length Smad4 of human origin
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Pancreatic adenocarcinoma
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Nuclear
Synonyme:Mothers against decapentaplegic homolog 4, (Small) Mothers Against Decapentaplegic, Deleted in Pancreatic Carcinoma, Deleted in pancreatic carcinoma locus 4, Deletion target in pancreatic carcinoma 4, DPC 4, DPC4, hSMAD4, JIP, MAD homolog 4, MAD mothers against decapentaplegic Drosophila homolog 4, MAD mothers against decapentaplegic homolog 4, MADH 4, MADH4, Med, Medea, Mothers against decapentaplegic homolog 4, Mothers against DPP homolog 4, OTTHUMP00000163548, Smad 4, SMAD family member 4, SMAD mothers against DPP homolog 4.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

SMAD family member 4, also known as SMAD4, is a protein that is involved in cell signaling. It functions as a transcription factor and is a member of the TGFbeta superfamily. It is mutated in many cancers: multiploid colorectal cancer, pancreatic carcinoma and juvenile polyposis syndrome (JPS) which includes a greater risk of developing gastrointestinal cancers, in particular colon cancer. Smad 4 is a member of the Mothers Against Dpp (MAD)-related family of proteins.

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