Technische Daten
Change(s) made:Complete revision
Status:In Vitro Diagnostic Use (IVD)
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human Mesothelin
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Zelluläre Lokalisation:Membranous, cytoplasmic
Synonyme:Mesothelin, MLSN, MES, CAK 1, CAK1, CAK1 antigen, Megakaryocyte potentiating factor, Mesothelin isoform 1 precursor, MPF, MSLN, Pre pro megakaryocyte potentiating factor, SMR, SMRP, Soluble MPF mesothelin related protein.
Verfügbar in folgenden Ländern:worldwide

Mesothelin is a 40 kDa protein that is expressed on the cell surface of normal mesothelial cells lining the pleura, peritoneum and pericardium. Its biological function is not known. Mesothelin is overexpressed in several human tumors, including mesothelioma, ovarian cancer, pancreatic adenocarcinoma and cholangiocarcinoma. Mesothelin may form a strong complex with MUC16 which may facilitate the implantation and peritoneal spread of tumors by cell adhesion leading to metastasis.


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