Technische Daten
Change(s) made:Complete revision
Status:In Vitro Diagnostic Use (IVD)
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human MUM1
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Zelluläre Lokalisation:Nuclear
Kontrolle:Lymphoma, tonsil
Synonyme:EXPAND1 , FLJ14868 , FLJ22283 , HSPC211 , Melanoma associated antigen (mutated) 1 , Melanoma ubiquitous mutated protein , MGC131891 , MGC163315 , MUM 1 , MUM-1 , MUM1 , MUM1_HUMAN , Mutated melanoma associated antigen 1 , Mutated melanoma-associated antigen 1 , Protein expandere , PWWP domain containing protein MUM1 , PWWP domain-containing protein MUM1.
Verfügbar in folgenden Ländern:worldwide

MUM1 is a transcriptional activator that binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter as well as immunoglobulin lambda light chain enhancer, together with PU.1. It is expressed in the nuclei and cytoplasm of plasma cells, a subset of B-cells in the light zone of the germinal center, activated T-cells and a wide spectrum of related hematolymphoid neoplasms derived from these cells. This antibody is used to detect lymphoid malignancies and Hodgkin’s and Reed-Sternberg cells of classic Hodgkin’s disease in combination with anti-CD30.