Technische Daten
Change(s) made:Complete revision
Status:Research Use Only (RUO)
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human MMP-9
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Zelluläre Lokalisation:Cytoplasmic
Kontrolle:Spleen, breast carcinoma
Synonyme:Matrix metalloproteinase-9 precursor, MMP-9, MMP9, MMP 9, 92 kDa type IV. Collagenase, 92 kDa gelatinase, Gelatinase B, GELB, Matrix metalloproteinase 9
Verfügbar in folgenden Ländern:worldwide

MMP9 is an enzyme that belongs to the matrix metalloproteinase family and is involved in the breakdown of extracellular matrix in normal physiological processes. MMPs are considered to play an important role in wound healing, apoptosis, bone elongation, embryo development, angiogenesis and tissue remodeling, in diseases such as multiple sclerosis, Alzheimer's, lupus, arthritis, periodontis, atherosclerosis, tissue ulceration, and in cancer cell invasion and metastasis. These enzymes are very potent when active, and are associated with extracellular space inhibitors called TIMPs (tissue inhibitors of matrix metalloproteinases). TIMPs have been shown to block tumor cell invasion suggesting that they act as metastasis suppressor genes.