Technische Daten
Status:Research Use Only (RUO)
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human LIN28A protein
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Zelluläre Lokalisation:Cytoplasmic, nuclear
Kontrolle:Germ cell tumor
Change(s) made:Complete revision
Synonyme:Lin 28 , Lin28A , Lin 28 homolog (C. elegans) , Lin 28 homolog A , Lin 28 homolog , Lin-28,y, Lin-28 homolog (C. elegans) , Lin-28 homolog A , Lin-28A , Lin28 , Lin28a , LN28A_HUMAN , Protein lin-28 homolog A , RNA binding protein lin 28 , RNA binding protein lin-28 , Tex17 , ZCCHC1 , Zinc finger CCHC domain containing 1 , Zinc finger CCHC domain containing protein 1 , Zinc finger CCHC domain-containing protein 1 , AL024421 , CSDD1.
Verfügbar in folgenden Ländern:worldwide

LIN28 is a RNA-binding protein acting as a 'translational enhancer' which drives specific mRNAs to polysomes and thus increases the efficiency of protein synthesis. It controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle.