Isocitrate dehydrogenase 1/IDH1

Rb, 1 ml RTU

Artikelnummer:2-IS003-07
Menge:
Technische Daten
Reaktivität AK:Human, Mouse, Rabbit, Rat, please ask for further reactivities.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human IDH1/Isocitrate dehydrogenase
Anwendung AK:IHC(p*) *reported as working on paraffin,IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Zelluläre Lokalisation:Cytoplasmic, peroxisome
Kontrolle:Human breast carcinoma tissue
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Synonyme:Cytosolic NADP isocitrate dehydrogenase, Cytosolic NADP-isocitrate dehydrogenase, ICDH, IDCD, IDH, IDHC, Idh1, IDHC_HUMAN, IDP, IDPC, Isocitrate dehydrogenase [NADP] cytoplasmic, Isocitrate dehydrogenase 1 (NADP+) soluble, NADP dependent isocitrate dehydrogenase cytosolic, NADP dependent isocitrate dehydrogenase peroxisomal, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, PICD.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

Isocitrate dehydrogenase 1 is a cytoplasmic enzyme that catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming alpha-ketoglutarate and CO2 in a two step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of alpha-ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. It is expressed in a wide range of species and also in organisms that lack a complete citric acid cycle.

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