Immunoglobulin G4/IgG4

Rb, 3 ml RTU

Artikelnummer:2-IM041-10
Menge:
Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Cytoplasmic
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of hinge region of human IgG4, no cross-reaction with IgG1, IgG2, IgG3
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Tonsil
Synonyme:IgG
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

Immunoglobulin G is the most abundant antibody isotype found in the circulation. Human IgG4, one of four subclasses of IgG, contains a gamma 4 heavy chain and a hinge region that is shorter than that of IgG1. Its two
primary effector functions are activating complements and binding to the FcgR of effector cells to initiate phagocytosis. Human IgG4 accounts for less than 6% of the total IgG serum level.

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