IgG4
Rb
Artikelnummer: | IM041-H_RUO |
Technische Daten
Change(s) made: | Complete revision | Status: | Research Use Only (RUO) | Spezies: | Rabbit | Ig Unterklasse: | IgG | Immunogen: | Synthetic peptide of hinge region of human IgG4, no cross-reaction with IgG1, IgG2, IgG3 | Vorbehandlung: | ProTaqs® Antigen Enhancer I (Cat. No. 401602092) | Zelluläre Lokalisation: | Cytoplasmic | Kontrolle: | Tonsil | Synonyme: | Immunoglobulin G4/IgG4 | Verfügbar in folgenden Ländern: | worldwide |
Beschreibung
Immunoglobulin G is the most abundant antibody isotype found in the circulation. Human IgG4, one of four subclasses of IgG, contains a gamma 4 heavy chain and a hinge region that is shorter than that of IgG1. Its two primary effector functions are activating complements and binding to the FcgR of effector cells to initiate phagocytosis. Human IgG4 accounts for less than 6% of the total IgG serum level.
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