Hypoxia inducible factor 1 alpha/HIF1A

Rb, 7 ml RTU

Artikelnummer:2-HY033-13
Menge:
Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Zelluläre Lokalisation:Cytoplasmic, nuclear
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human HIF-1 Alpha near C-terminus
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Kontrolle:Breast cancer
Synonyme:hypoxia-inducible factor 1, alpha subunit isoform 1, Hypoxia-inducible factor 1 alpha, HIF-1 alpha, HIF1 alpha, HIF-1a, HIF-1alpha, ARNT-interacting protein, Member of PAS protein1, Basic-helix-loop-helix-PAS protein MOP1, Hypoxia-inducible factor -1 Alpha.
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

HIF-1 alpha is a subunit of hypoxia-inducible factor 1 alpha and functions as a master transcriptional regulator that is essential for various biological prosecces like angiogenesis which is required for tumor growth, systemic O2 homeostasis, cardiovascular development and cell survival. Overexpression has been shown to be associated with nonpapillary renal carcinomas.

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