HIF1A
Rb
Artikelnummer: | HY033-H_RUO |
Technische Daten
Status: | Research Use Only (RUO) | Spezies: | Rabbit | Ig Unterklasse: | IgG | Immunogen: | Synthetic peptide of human HIF-1 Alpha | Vorbehandlung: | ProTaqs® Antigen Enhancer I (Cat. No. 401602092) | Zelluläre Lokalisation: | Cytoplasmic, nuclear | Kontrolle: | Breast cancer | Change(s) made: | Complete revision | Synonyme: | hypoxia-inducible factor 1, alpha subunit isoform 1, Hypoxia-inducible factor 1 alpha, HIF-1 alpha, HIF1 alpha, HIF-1a, HIF-1alpha, ARNT-interacting protein, Member of PAS protein1, Basic-helix-loop-helix-PAS protein MOP1, Hypoxia-inducible factor -1 Alpha. | Verfügbar in folgenden Ländern: | worldwide |
Beschreibung
HIF-1 alpha is a subunit of hypoxia-inducible factor 1 alpha and functions as a master transcriptional regulator that is essential for various biological prosecces like angiogenesis which is required for tumor growth, systemic O2 homeostasis, cardiovascular development and cell survival. Overexpression has been shown to be associated with nonpapillary renal carcinomas.
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