HIF1A

Rb

Artikelnummer:HY033-H_RUO
Menge:
Technische Daten
Status:Research Use Only (RUO)
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human HIF-1 Alpha
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092)
Zelluläre Lokalisation:Cytoplasmic, nuclear
Kontrolle:Breast cancer
Change(s) made:Complete revision
Synonyme:hypoxia-inducible factor 1, alpha subunit isoform 1, Hypoxia-inducible factor 1 alpha, HIF-1 alpha, HIF1 alpha, HIF-1a, HIF-1alpha, ARNT-interacting protein, Member of PAS protein1, Basic-helix-loop-helix-PAS protein MOP1, Hypoxia-inducible factor -1 Alpha.
Verfügbar in folgenden Ländern:worldwide
Beschreibung

HIF-1 alpha is a subunit of hypoxia-inducible factor 1 alpha and functions as a master transcriptional regulator that is essential for various biological prosecces like angiogenesis which is required for tumor growth, systemic O2 homeostasis, cardiovascular development and cell survival. Overexpression has been shown to be associated with nonpapillary renal carcinomas.

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