Glypican 3

1G12, Ms

Artikelnummer:GL174-H
Menge:
Technische Daten
Status:In Vitro Diagnostic Use (IVD)
Spezies:Mouse
Ig Unterklasse:IgG1
Immunogen:Glypican-3
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092) or ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Cytoplasmic
Kontrolle:Hepatocellular carcinoma (HCC)
Change(s) made:Complete revision
Synonyme:GPC3, DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1
Verfügbar in folgenden Ländern:worldwide
Beschreibung

Glypican-3 is a memer of glypican family of heparan sulfate proteoglycans that are anchored to the cell-surface via a covalent linkage to glycosylphosphatidylinositol. Glypicans can modify cell signaling pathways and contribute to cellular proliferation and tissue growth. GPC3 is a useful tumor marker for the diagnosis of hepatocellular carcinoma, hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor.

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