Estrogen receptor alpha
Rb, 0.5 ml Conc.
Technische Daten
Lagerung AK: | Store at 2 - 8 °C. Do not use after expiration date indicated on the vial. | Kontrolle: | Breast carcinoma, breast | Zelluläre Lokalisation: | Nuclear | Fixierung: | 1) NOTOXhisto 2) Formalin | Anwendung AK: | IHC(p),IHC(f) | Immunogen: | Synthetic peptide of human Estrogen Receptor alpha protein | Ig Unterklasse: | IgG | Spezies: | Rabbit | Klon: | Polyclonal | Format AK: | Concentrate | Reaktivität AK: | Human, others not tested. | Synonyme: | ER alpha, ER, ESR 1, ESRA, Estradiol receptor, Estrogen nuclear receptor alpha, Major ORF, NR3A1, Nuclear receptor subfamily 3 group A member 1 | Verfügbar in folgenden Ländern: | world wide (except US) | Status: | IVD |
Beschreibung
The antibody is specific for 67 kDa polypeptide of human nuclear estrogen receptor. Specific staining is restricted to nuclei of carcinoma cells and hyperplastic mammary epithelium. A positive tissue control should contain estrogen receptor positive cells in both breast adenocarcinoma and norme breast sections.
Literatur
[1] Lim E, Tarulli G, Portman N, et al. (2016): Pushing
estrogen receptor around in breast cancer. Endocr Relat
Cancer. 23(12): T227-T241.
[2] Farzaneh S, & Zarghi A (2016): Estrogen Receptor
Ligands: A Review (2013-2015). Sci Pharm. 84(3):409-
427.
[3] Gown AM (2008): Current issues in ER and HER2
testing by IHC in breast cancer. Mod Pathol. 21 Suppl
2:S8-S15.
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