Estrogen receptor alpha

Rb, 1 ml RTU

Artikelnummer:2-ES006-07
Menge:
Technische Daten
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Kontrolle:Breast carcinoma, breast
Zelluläre Lokalisation:Nuclear
Fixierung:1) NOTOXhisto 2) Formalin
Anwendung AK:IHC(p),IHC(f)
Immunogen:Synthetic peptide of human Estrogen Receptor alpha protein
Ig Unterklasse:IgG
Spezies:Rabbit
Klon:Polyclonal
Format AK:Ready-to-use
Reaktivität AK:Human, others not tested.
Synonyme:ER alpha, ER, ESR 1, ESRA, Estradiol receptor, Estrogen nuclear receptor alpha, Major ORF, NR3A1, Nuclear receptor subfamily 3 group A member 1
Verfügbar in folgenden Ländern:world wide (except US)
Status:IVD
Beschreibung

The antibody is specific for 67 kDa polypeptide of human nuclear estrogen receptor. Specific staining is restricted to nuclei of carcinoma cells and hyperplastic mammary epithelium. A positive tissue control should contain estrogen receptor positive cells in both breast adenocarcinoma and norme breast sections.

Literatur

[1] Lim E, Tarulli G, Portman N, et al. (2016): Pushing estrogen receptor around in breast cancer. Endocr Relat Cancer. 23(12): T227-T241.
[2] Farzaneh S, & Zarghi A (2016): Estrogen Receptor Ligands: A Review (2013-2015). Sci Pharm. 84(3):409- 427.
[3] Gown AM (2008): Current issues in ER and HER2 testing by IHC in breast cancer. Mod Pathol. 21 Suppl 2:S8-S15.

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