Epstein Barr Virus EBNA 1

1H4, Rt

Artikelnummer:EP076-H_RUO
Menge:
Technische Daten
Status:Research Use Only (RUO)
Spezies:Rat
Ig Unterklasse:IgG2a
Immunogen:N/A
Vorbehandlung:ProTaqs® Antigen Enhancer I (Cat. No. 401602092) or ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Cytoplasmic
Kontrolle:Epithelial carcinoma
Change(s) made:Complete revision
Synonyme:EBV, human herpesvirus 4, HHV-4, BMRF1, DNA polymerase accessory protein, Early antigen protein
Verfügbar in folgenden Ländern:worldwide
Beschreibung

Epstein Barr Virus (EBV) has oncogenic properties and the capacity to transform normal, resting B-cells into permanent lymphoblastoid cell lines. Six virus-encoded Epstein Barr nuclear antigens (EBNA) and three latent membrane proteins (LMP) are known. One important EBV-associated epithelial tumor is the nasopharyngeal carcinoma (NPC). EBV expresses only the proteins EBNA-1 and LMP-1 in NPC tumor cells. Tumors morphologically/histologically similar to NPC can also be found in the stomach, oesophagus, salivary glands, lung and in thymus glands.

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