ERG

Rb, 1 ml RTU

Artikelnummer:2-ER010-07
Menge:
Technische Daten
Reaktivität AK:Human, others not tested.
Format AK:Ready-to-use
Klon:Polyclonal
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human ERG C-terminal
Anwendung AK:IHC(p),IHC(f)
Fixierung:1) NOTOXhisto 2) Formalin
Zelluläre Lokalisation:Nuclear
Kontrolle:Human prostate adenocarcinoma tissue
Lagerung AK:Store at 2 - 8 °C. Do not use after expiration date indicated on the vial.
Synonyme:ETS related gene
Verfügbar in folgenden Ländern:world wide
Status:RUO
Beschreibung

ERG, also known as ETS related gene, is a member of the ETS family of transcription factors that play important roles in cell development, differentiation, proliferation, apoptosis and tissue remodeling. The antibody labels endothelial cells, lymphocytes, and prostate
cancer cells. Overexpression of ERG is associated with prostate cancer. Furthermore, the TMPRSS2-ERG fusion caused by translocations and interstitial deletions, is implicated in aggressive forms of prostate cancer. EWS-ERG, or EWS-Fli-1 fusion, is a characteristic of EwingÕs sarcoma.

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