Desmoglein 3

Rb

Artikelnummer:DE082-H_RUO
Menge:
Technische Daten
Status:Research Use Only (RUO)
Spezies:Rabbit
Ig Unterklasse:IgG
Immunogen:Synthetic peptide of human Desmoglein 3
Vorbehandlung:ProTaqs® Antigen Enhancer IV (Cat. No. 401602392)
Zelluläre Lokalisation:Membranous
Kontrolle:Skin, cervical squamous cell carcinoma
Change(s) made:Complete revision
Synonyme:130 kD pemphigus vulgaris antigen, Balding, CDHF 6, CDHF6, Desmoglein 3 precursor, Desmoglein3, DKFZp686P23184, DSG 3, DSG3, DSG-3, Pemphigus vulgaris antigen, PVA.
Verfügbar in folgenden Ländern:worldwide
Beschreibung

Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. In the skin epidermis desmoglein 3 is expressed in the basal lower layers of the epidermis. Desmoglein 3 serves as a prognostic marker of esophageal squamous cell carcinoma (ESCC), and may even be involved in the progression of ESCC.

Literatur

Kontakt